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Способ моделирования ятрогенного повреждения желчевыводящих протоков на экспериментальном животном
专利权人:
Federalnoe gosudarstvennoe byudzhetnoe voennoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya Voenno-meditsinskaya akademiya im. S.M. Kirova Ministerstva oborony Rossijskoj Federatsii (VMedA)
发明人:
Majstrenko Nikolaj Anatolevich,Майстренко Николай Анатольевич,Romashchenko Pavel Nikolaevich,Ромащенко Павел Николаевич,Aliev Arsen Kamilevich,Алиев Арсен Камильевич
申请号:
RU2017100116
公开号:
RU0002664622C2
申请日:
2017.01.09
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention relates to experimental medicine and can be used for simulating iatrogenic bile duct injuries (IBDI) in pigs. Simulation is carried out in a pig. Method comprises sedation of an animal, fixation on the laboratory table in the supine position with spread out and fixed limbs, anesthesia and infusion therapy. Carboxy-peritoneum is further formed with Veres needle over the umbilicus with a partial pressure of carbon dioxide of 14 mm Hg at conditions of combined general anesthesia with intubation of the trachea and artificial ventilation of the lungs. 4 trocars are introduced for manipulators: above the umbilicus – a trocar with a diameter of 10 mm, under the ensisternum – 2 trocars with a diameter of 5 mm at a distance of 3 cm from each other, and in the right hypochondrium region – a trocar with a diameter of 5 mm. Then, with the help of a soft clamp and a dissector, a choledochous duct is separated from the hepatoduodenal ligament at the point of cystic duct confluence into the common hepatic duct. Clipator with a diameter of 10 mm is inserted through a separate puncture of the anterior abdominal wall under the ensisternum with a diameter of 10 mm. Choledochous is clipped, with fixation of 2 clips in the proximal direction from the point of cystic duct confluence and of 1 clip in the distal direction. Choledochous duct is further completely transected below the point of confluence into the cystic duct, between the 2 proximal clips and the 1 distal clip. In case of mechanical damage, the choledochous duct is transected by means of endoscopic scissors. In case of thermal damage, it is transected by means of an L-shaped electrode for dissection under the action of a monopolar diathermic generator, installed in dissection mode at a given current strength of 70A for all diathermic influences.EFFECT: proposed original model while minimizing the trauma and the magnitude of blood loss is comparable with the IBDI in humans when performing
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中国工程科技知识中心
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