The present invention relates to a composition containing a chemokine, especially an interferon-inducible T-cell alpha chemoattractant (ITAC) so as to decrease the gene expression of a factor related to melanin pigment formation in a melanin-forming cell, thereby exhibiting a skin whitening effect.本發明涉及一種組合物,所述組合物含有趨化因子,尤其含有干擾素誘導性T細胞α趨化因子而減少黑色素形成細胞中的黑色素生成相關因子的基因表現,從而能夠獲得美白皮膚的效果。