An osteosynthesis plate suitable for the fixation of fractures of the distal fibula/lateral malleolus includes a twisted distal portion and a proximal portion with a constant orientation that is perfectly congruent with the actual geometry of the distal fibula and it can be positioned with a rear orientation in the distal region. An osteosynthesis plate according to the invention favours, among other things, the restoration of the length and bone rotation and the peroneal-talar joint congruence, decreases tissue sufferance and facilitates the positioning of syndesmosis screws.