Mary J. C. HENDRIX,Richard E. B. Seftor,Elisabeth A. Seftor
申请号:
US16747419
公开号:
US20200239561A1
申请日:
2020.01.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to combination therapeutic agents comprising an anti-cancer drug and an anti-Nodal agent for use in decreasing, suppressing and/or abrogating manifestation or appearance of cancer drug resistance in a cancer subject in need thereof. The anti-Nodal agent decreases, suppresses and/or abrogates cancer drug resistance to the anti-cancer drug in the cancer subject. A pharmaceutical composition comprising an anti-Nodal agent for use in decreasing, suppressing and/or abrogating manifestation or appearance of cancer drug resistance in a cancer subject in need thereof is disclosed. A method for prognosis of cancer patient and a diagnostic kit are also disclosed.