Methods systems, computer-readable media, techniques and processes for crown or prosthesis manipulation in dental prosthesis design include presenting a 3D model of a multi-tooth prosthesis relative to an area to be reconstructed. An operator may manipulate one or more prosthetic teeth in that 3D model in order to alter the overall shape of the prosthesis. The techniques may also include the determination of occlusion with respect to antagonist teeth-of the entire 3D model of the prosthesis and/or of individual 3D models of prosthetic teeth in the model. The position or shape of the 3D model of the prosthesis may be modified based on the occlusion.