An emergency responder alert system. The emergency responder alert system includes a housing having a container affixed thereto, wherein the container includes a bottom, a sidewall, and an open end defining an interior volume. A power source is connected to the housing and provides power thereto. The system further includes indicia having a fastener on a rear side, wherein a front side thereof is reflective and a light source to illuminate the indicia. A speaker is disposed on the housing and is connected to a microprocessor disposed therein. The microprocessor includes a logic that activates when a control on the housing is actuated. The logic contacts emergency services to allow two-way communication via the speaker, disengages a door lock mechanism, illuminates the light source, and sends an alert to a pre-determined third-party.