A cell death inducer or cell death promoter selective for activated T cells and / or B cells, comprising 25-hydroxycholesterol or an analogue cholesterol thereof as an active ingredient
The object of the present invention is to activate activated T cells and / or B cells which are effective for the prevention or treatment of a disease showing an enhanced or abnormal immune function by activated T cells and / or activated B cells. It is providing a cell death inducer or a cell death promoter. A cell death inducer or a cell death promoter selective for activated T cells and / or B cells, comprising 25-hydroxycholesterol or its analog cholesterol as an active ingredient. 本発明の課題は、活性化Ｔ細胞及び／又は活性化Ｂ細胞による免疫機能の亢進又は異常を示す疾患の予防又は治療に効果的な、活性化されたＴ細胞及び／又はＢ細胞選択的な細胞死誘導剤又は細胞死促進剤を提供することにある。 ２５－ヒドロキシコレステロール又はその類縁体コレステロールを有効成分として含有してなる、活性化されたＴ細胞及び／又はＢ細胞に選択的な細胞死誘導剤又は細胞死促進剤。
