Adam Platt,Jianmei Wang,Guiyuan Lei,Laurent Essioux,Wei-min Liu,P. Mickey Williams
申请号:
US13154158
公开号:
US20120009177A1
申请日:
2011.06.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides methods, compositions, and kits relating to gene product biomarkers where gene expression levels are correlated with therapeutic response of rheumatoid arthritis patients to treatment with an IL-6 receptor antagonist, such as an IL6-R antibody. The methods, compositions, and kits of the invention can be used to identify rheumatoid arthritis patients who are likely, or not likely, to respond to IL-6 receptor antagonist treatments.