Aarthi Chandrasekaran,Shiladitya Sengupta,David A. Berry,Kristine Holley,Ganlin Zhao,Ram Sasisekharan
申请号：
US11171490
公开号：
US08529889B2
申请日:
2005.06.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to compositions and methods for the modulation of the permeability of the epithelial cell barrier complex. In particular, the invention provides compositions and methods for using polysaccharides, preferably glycosaminoglycans, and agents that modify cell surface glycosaminoglycans, preferably glycosaminoglycan-degrading enzymes to modulate intercellular junctions. The compositions and methods provided can be used to facilitate the delivery of biologically active molecules.
