Stephen M. G. Gottschalk;Zakaria Grada;Gianpietro Dotti;Nabil Ahmed;Malcolm Brenner;Claudia Rossig
发明人:
Malcolm Brenner,Gianpietro Dotti,Nabil Ahmed,Claudia Rossig,Stephen M. G. Gottschalk,Zakaria Grada
申请号：
US13820931
公开号：
US09493740B2
申请日:
2011.09.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention concerns immunotherapy for cancers having cells that comprise the ganglioside GD2 antigen. In specific embodiment, T cells having a chimeric receptor that targets GD2 is employed. In particular cases, the chimeric receptor comprises antibody, cytoplasmic signaling domain from the T cell receptor, and/or costimulatory molecule(s).
