#$%^&*AU2020101850A420200924.pdf#####ABSTRACT The invention relates to the field of pharmacology, in particular to a composition composed of extract of Paulownia fortunei extract, Chromium Polynicotinate, Curcuma longa L. root extract, berberine hydrochloride and green coffee bean extract. Pharmacological and toxicological experiments of the mouse diabetes model proves that the pharmaceutical composition of this invention has very ideal hypoglycemic effect and good administration safety. In addition, the pharmaceutical composition of the present invention is for treating diabetes. The medicine of the invention can be made into various oral dosage forms, thus it is convenient to carry and take.