Torsten Heilmann,Heiko Noack,Christian Richter,Sabine Post
申请号：
US13819538
公开号：
US20130345296A1
申请日:
2011.08.31
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates a pharmaceutical composition comprising a taxane and an inhibitory compound capable of inhibiting the enzyme acetaldehyde dehydrogenase e.g. disulfiram. The pharmaceutical compositions of the invention can be used to coat medical devices such as implants. Such implant can be an expansible hollow part, having at least one opening, which consists of an elastic biocompatible material that comprises elongated micro-cavities in its surface. Medical devices coated with a pharmaceutical composition of the invention exhibit an enhanced transfer of taxane from the surface of said medical device into the target tissue.
