Pamula Vamsee K.,Sista Ramakrishna,Srinivasan Vijay,Pollack Michael G.,Eckhardt Allen
申请号:
US201615266693
公开号:
US10139403(B2)
申请日:
2016.09.15
申请国别(地区):
美国
年份:
2018
代理人:
Illumina, Inc.
摘要:
The invention provides a method of circulating magnetically responsive beads within a droplet in a droplet actuator. The invention also provides methods for splitting droplets. The invention, in one embodiment, makes use of a droplet actuator with top and bottom substrates, a plurality of magnetic fields respectively present proximate the top and bottom substrates, wherein at least one of the magnet fields is selectively alterable, and a plurality of droplet operations electrodes positioned along at least one of the top and bottom surfaces. A droplet is positioned between the top and bottom surfaces and at least one of the magnetic fields is selectively altered.