Johns Hopkins University;The University of North Carolina at Chapel Hill
发明人:
申请号:
EP19218983.5
公开号:
EP3666285A2
申请日:
2013.10.29
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus.