602075 Provided is a sustained-release oral dosage form suitable for twice-a-day administration comprising a matrix which contains a viscosity modifier in an amount from about 1 to about 10 percent by weight of the dosage form selected from sodium alginate, hydroxypropylmethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, methylcellulose, carboxymethylcellulose, sodium carboxymethylcellulose, polyvinylpyrrolidone, crosslinked polyacrylic acid, gelatin, pectins, gums, polyethylene oxides, Konjac flour, carrageenan, xanthan gum, and mixtures thereof and comprises coated granules containing hydrocodone, wherein the core of the coated granules contains less than 5% fat/wax. The dosage form can have a release profile such that 6 hours following administration, less than about 80 percent of the hydrocodone is released. In addition, the dosage form may have alcohol and/or crush resistance
