COMBINED THERAPY AGAINST MALIGNANT TUMOR WITH ANTAGONIST IAP AND MOLECULE AGAINST PD-1

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专利权人:

ДЕБИОФАРМ ИНТЕРНЭШНЛ C.A.

发明人:

Воньо, Грегуар,Видеманн, Норберт,Гавилле, Бруно,Шильдергемайн Альтман, Серхио Адриан

申请号：

EA202091539

公开号：

EA202091539A1

申请日:

2018.12.21

申请国别(地区):

EA

年份:

2020

代理人:

摘要：

Disclosed is the use of an IAP antagonist for pretreating a human subject diagnosed with a cancer to enhance the likelihood that a subsequent treatment with an anti-PD-1 molecule results in an anti-cancer response or to enhance the responsiveness of the subject's cancer to the subsequent treatment with the anti-PD-1 molecule. Also encompassed are methods of treatment of a subject's cancer, the methods comprising pretreatment of the subject with an IAP antagonist and subsequent treatment of the subject with an anti-PD-1 molecule.

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