PRODUCTION OF OVERSIZED ADENO-ASSOCIATED VECTORS

• 收藏
• 分享

专利权人:

GENZYME CORPORATION

发明人:

KYOSTIO-MOORE, Sirkka,SOUZA, David,VINCENT, Karen

申请号：

PH12017501836

公开号：

PH12017501836A1

申请日:

2017.10.06

申请国别(地区):

PH

年份:

2018

代理人:

摘要：

Provided herein are methods for producing an adeno-associated virus (AAV) particle containing an oversized recombinant AAV genome (e.g., greater than 4.7 kb). In some aspects, the invention provides AAV particles and AAV vectors comprising oversized rAAV genomes. Producer cell lines to produce AAV particles comprising oversized genomes are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/