Systems, devices, and methods for removing and/or treating obstructions in the vascular channels, such as blood clots, are provided. The systems may include a capture sock device including a shaft defining a lumen； and a mouth coupled to the shaft. The mouth includes a distal end portion defining a distal opening and is sized and configured to move between a collapsed configuration and an expanded configuration within a body channel. The mouth is formed of a mesh having porosity large enough to allow blood flow to pass through it but small enough to prevent an obstruction or a fragment of the obstruction from escaping from the mouth back into the body channel. In some embodiments, the mesh is folded to create at least two mesh layers at least at the distal opening to create a smooth atraumatic edge. In some embodiments, the system further includes a trap and/or retriever assembly.
