Timothy P. Heffernan,Carlo Toniatti,Jeffrey Kovacs,Virginia Giuliani,Nakia Spence,Maria Emilia Di Francesco,Christopher A. Bristow
申请号:
US14791307
公开号:
US20160058759A1
申请日:
2015.07.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed herein are methods of treating a subject having an altered NRF2/KEAP1 pathway, and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject.