The present invention, stereoisomers thereof, including acceptable derivatives novel compounds of formula (I), their pharmaceutically, tautomeric forms, the S-isomer and R, polymorphs, prodrugs, metabolites, salts or solvate of. The invention relates to a process for synthesizing a solvate of acceptable derivative novel compounds of Formula I, their pharmaceutically, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, or salts.本発明は、式(I)の新規化合物、それらの薬学的に許容可能な誘導体、互変異性型、R及びS異性体を含む立体異性体、多形、プロドラッグ、代謝産物、塩又はそれらの溶媒和物に関する。発明はまた、式Iの新規化合物、それらの薬学的に許容可能な誘導体、互変異性型、立体異性体、多形、プロドラッグ、代謝産物、塩又はそれらの溶媒和物の合成プロセスに関する。