A staple cartridge assembly (40) and a medical anastomat using the staple cartridge assembly (40). The staple cartridge assembly (40) comprises a staple cartridge (41), a staple anvil (42) and a cutter (45). The cutter (45) comprises a first end portion (451), a second end portion (452) and a cutting portion disposed between the first end portion (451) and the second end portion (452). The cutting portion is provided with a blade (453). The staple cartridge assembly (40) further comprises a rotation shaft (50) and an auxiliary closure member connected to the rotation shaft (50). The rotation shaft (50) is disposed at the proximal end of the staple cartridge assembly (40) relative to the blade (453). The staple cartridge assembly (40) is further provided with a driving component (51) capable of driving the rotation shaft (50) to rotate. The driving component (51) drives the rotation shaft (50) to drive the auxiliary closure member to move in the process in which the staple cartridge assembly (40) is converted from an initial state to a closed state. When at least the staple cartridge assembly (40) is in the closed state, one end surface of the auxiliary closure member leans against the staple anvil (42), to apply an action force to the staple anvil (42) to drive the staple anvil (42) to be closed towards the staple cartridge (41). The staple cartridge assembly (40) and the medical anastomat using the staple cartridge assembly (40) in the present invention can effectively reduce the tension force applied to an I-shaped cutter during use, and prevent the I-shaped cutter from being broken.
