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REGULATION OF BONE GROWTH USING ZEOLITE IN COMBINATION WITH BONE GRAFT SUBSTITUTES
专利权人:
发明人:
DERRICK JOHNS,MATTHEW GECK,PETER WHANG,JAMI HAFIZ
申请号:
IN7793/DELNP/2011
公开号:
IN2011DN07793A
申请日:
2011.10.11
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Medical implants such as bone graft substitutes that include one or more cations are delivered in a local environ ment to promote osteogenesis. Zeolite loaded with a metal cation in combination with an implant such as a bone graft substitute can be used as an implant in the body to regulate protein transcription and translation. Also disclosed are methods of promoting osteogenesis in a patient in need thereof methods for modulating bone formation and mineralization by implanting in a patient a medical implant comprising ion-exchangeable cations, and methods of regulating BMP gene expression in bone cells in a patient by controlling the delivery of certain cations through ion- exchange via a zeolite incorporated in a bone substitute implanted m a patient so that BMP gene expression can be upregulated or downregulated appropriately.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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