University of Florida Research Foundation, Incorporated;The UAB Research Foundation
发明人:
Zolotukhin, Sergei,Boye, Sanford L.,Boye, Shannon E.,Marsic, Damien,Muzyczka, Nicholas,Mendez-Gomez, Hector Ruben,Gamlin, Paul D.
申请号:
AU2018224044
公开号:
AU2018224044A1
申请日:
2018.02.21
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells.