The inventors discovered that a certain type of VCP inhibitor has a protective effect on corneal endothelial cells and corneal epithelial cells. Consequently, a composition for corneal protection is provided which contains the compound of expression (I) or an ester, oxide, pharmaceutically permissible salt or solvate thereof. As another embodiment, a pharmaceutical composition is provided for the treatment and/or prevention of corneal disease that contains the aforementioned compound. As a further embodiment, a composition for ocular perfusion containing the compound is provided. As yet a further embodiment, a composition for transplanted cornea preservation containing said compound is provided.
