Cheng-Chi Chang,Chiung-Nien Chen,Hsin-Yu Li,Min-Liang Kuo
申请号:
US13709534
公开号:
US20140162950A1
申请日:
2012.12.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a method for inhibiting peritoneal metastasis caused by gastric cancer cells in a subject in need thereof comprising administering to the subject a pharmaceutically effective amount of a connective tissue growth factor (CTGF), wherein the CTGF binds to an integrin α3β1 of the gastric cancer cells. The present invention also provides a method for predicting peritoneal metastasis caused by gastric cancer cells in a subject comprising providing a peritoneal tissue from the subject measuring a first expression amount of a connective tissue growth factor (CTGF) from the peritoneal tissue and comparing the first expression amount to a reference expression amount of the CTGF from a non-peritoneal metastasis gastric cancer tissue.