Phospholipid liposomes comprising at least one polyunsaturated fatty acid selected in the group consisting of dihomo-gamma-linolenic acid (DGLA), linoleic acid, gamma-linolenic acid, arachidonic acid, docosatetraenoic acid, a plant estrogen selected from equol, genistein, daidzein, glycitein; a compound able to increase cation capacity of the liposome selected from essential amino acids, carnitine and derivatives thereof; a stabilizer selected from cholesterol, cholesterol sulphate and stearylamine, for use in the treatment of alopecia, baldness, hair loss, and related pharmaceutical compositions containing them as active ingredients in association with suitable excipients and/or diluents.