KONTEATIS, Zenon, D. ZD,POPOVICI-MULLER, Janeta J-,TRAVINS, Jeremy J,.孔塔替斯,.泊泊威次-馬勒,.特維斯
申请号:
HK16112088.0
公开号:
HK1223923A
申请日:
2016.10.20
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
Provided are compounds of formula (I), wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl; one of X, Y and W is CH and the two others are N; and Z is H or —C(R1)(R2)(R3). The compounds are inhibitors of isocitrate dehydronenase 2 (IDH2) mutants useful for treating cancer.