ARNELLE, DERRICK,DEAVER, DANIEL,DEAN, REGINALD L., III,TODTENKOPF, MARK
申请号：
CA2714331
公开号：
CA2714331C
申请日:
2009.02.13
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to compoundsof Formula I or II, or pharmaceutically acceptablesalts, esters, or prodrugs thereof: (I) or (II) whichrelates to mophinan compounds useful as µ, .delta. and/or .kappa.receptor opioid compounds and pharmaceuticals containingsame that may be useful for mediating analgesia,combating drug addiction, alcohol addiction, drugoverdose, mental illness, bladder dysfunctions, neurogenicbladder, interstitial cystitis, urinary incontinence,premature ejaculation, inflammatory pain, peripherallymediated and neuropathic pain, cough, lung edema, diarrhea,cardiac disorders, cardioprotection, depression,and cognitive, respiratory, diarrhea, irritable bowelsyndrome and gastro-intestinal disorders, immunomodulation,and anti-tumor agents.
