The device comprises: - a tight test enclosure (14) for receiving the animal (16), - a means (20, 21) for thermally regulating the test enclosure (14), - a means (27) for renewing air in the test enclosure (14) at a controlled flow rate, - a pressure sensor (41) for measuring pressure difference between the air in the test enclosure and a reference, - a means (43) for deducing a volume of air inhaled or expired by the animal during one inhalation or expiration from a pressure measurement of the pressure sensor (41), The test enclosure (14) comprises a floor having at least three dry electrodes, insulated from each other, each electrode being intended for collecting an electrical signal resulting from the cardiac activity of the animal (16) when the animal is in contact with the electrode. The device comprises a means (51) for determining an electrocardiogram of the animal (16) by using three electrical signals collected by the at least three electrodes.