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Method for production of reprogrammed cell using chromosomally unintegrated virus vector
专利权人:
发明人:
Noemi Fusaki,Hiroshi Ban,Mamoru Hasegawa,Yoshikazu Yonemitsu
申请号:
US14812108
公开号:
US09695445B2
申请日:
2015.07.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
An objective of the present invention is to provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome. The present inventors discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrating viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments.
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