ANTI-AGF ANTIBODIES

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

ADAM, PAUL,BORGES,ERIC

申请号：

MYPI 2011002684

公开号：

MY150984A

申请日:

2009.12.11

申请国别(地区):

MY

年份:

2014

代理人:

摘要：

ANTIBODY MOLECULES, IN PARTICULAR FULLY HUMAN ANTIBODIES THAT BIND TO HUMAN 1GF-1 AND CROSS-REACT WITH IGF-2 SUCH THAT BINDING OF IGF-1 AND IGF-2 TO THE IGF-1 RECEPTOR IS PREVENTED AND IGF-1 RECEPTOR-MEDIATED SIGNALING IS INHIBITED. THE ANTIBODIES DO NOT BIND TO INSULIN AND THUS DO NOT AFFECT THE MITOGENIC PROPERTIES OF INSULIN THAT ARE MEDIATED BY ITS BINDING TO THE INSULIN RECEPTORS. THE ANTIBODIES ARE USEFUL FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES, IN PARTICULAR CANCER. (NO SUITABLE FIGURE)

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/