Nicholas Sinclair,Hugh McDermott,James Fallon,Thushara Perera,Arthur Wesley Thevathasan,Kristian Bulluss
申请号：
US16616017
公开号：
US20200138324A1
申请日:
2018.05.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for monitoring neural activity responsive to a stimulus in a brain, the method comprising: a. applying a first stimulus to one or more of at least one electrode implanted in the brain, the first stimulus comprising a first plurality of bursts of stimulation, b. detecting high frequency oscillations (HFOs) between about 200 Hz and about 500 Hz due to neuronal activity at one or more of the at least one electrode implanted in the brain at least partially during application of the first stimulus； c. determining one or more waveform characteristics of the HFOs； and d. generating a second stimulus comprising a second plurality of bursts of stimulation, wherein one or more waveform characteristics of the second stimulus is dependent on the one of more waveform characteristics of the HFOs； and e. applying the second stimulus to one or more of the at least one electrode implanted in the brain.
