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COMPOSITIONS AND METHODS FOR TREATING KIDNEY DISORDERS
专利权人:
Вектус Байосистемс Пти Лимитед (AU)
发明人:
ДАГГЕН Карен Аннетт (AU)
申请号:
RU2011114857/15
公开号:
RU2011114857A
申请日:
2009.10.16
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method for the prophylactic or therapeutic treatment of chronic kidney disease in a subject, comprising administering to a subject at risk of developing chronic kidney disease or a subject having chronic kidney disease a composition comprising a pharmaceutically effective amount of a vasoactive intestinal peptide (VIP) or one or more functional fragments VIPs selected from VIP (10-28), VIP (4-12), VIP (4-16), VIP (4-20), VIP (4-24), VIP (6-10), VIP (6- 12), VIP (6-16), VIP (6-20), VIP (6-24) or their conservative substitutions. 2. A method for the prophylactic or therapeutic treatment of renal failure in a subject, comprising administering to a subject at risk of developing renal failure, or to a subject having renal failure, a composition comprising a pharmaceutically effective amount of a vasoactive intestinal peptide (VIP) or one or more functional VIP fragments selected from VIP (10-28), VIP (4-12), VIP (4-16), VIP (4-20), VIP (4-24), VIP (6-10), VIP (6-12), VIP ( 6-16), VIP (6-20), VIP (6-24) or their conservative substitutions. 3. A method for the prophylactic or therapeutic treatment of kidney fibrosis in a subject, comprising administering to a subject at risk of developing kidney fibrosis or to a subject having kidney fibrosis a composition comprising a pharmaceutically effective amount of a vasoactive intestinal peptide (VIP) or one or more functional VIP fragments selected from VIP (10-28), VIP (4-12), VIP (4-16), VIP (4-20), VIP (4-24), VIP (6-10), VIP (6-12), VIP ( 6-16), VIP (6-20), VIP (6-24) or their conservative substitutions. 4. The method of claim 1, wherein chronic renal disease or renal failure is associated with kidney fibrosis. The method according to claim 3, where the treatment warns, slows down and�1. Способ профилактического или терапевтического лечения хронического почечного заболевания у субъекта, включающий введение субъекту, подверженному риску развития хронического почечного заболевания, или субъекту, имеющему хроническое почечно
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