There is disclosed a materials delivery system (30,50) for use with a surgical stapling instrument having at least one jaw including a knife slot (32,62). The materials delivery system includes a series of treatment material receiving pockets (36,52,54,96,98) positioned adjacent the knife slot (32,62) such that a portion of each pocket is open to the knife slot. A source of treatment material (38,56) is positioned within the pockets (36,52,54,96,98) such that passage of the knife blade (108) adjacent to the pockets repeatedly coats the knife blade with the treatment material.