Brendan P. ECKELMAN,John C. TIMMER,Peter L. NGUY,Grant B. GUENTHER,Quinn DEVERAUX
申请号：
US15875010
公开号：
US20180179264A1
申请日:
2018.01.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and second polypeptide comprising of at least one the following: an Fc polypeptide or an amino acid sequence that is derived from an Fc polypeptide； a cytokine targeting polypeptide or a sequence derived from a cytokine targeting polypeptide； a WAP domain containing polypeptide or a sequence derived from a WAP containing polypeptide； and an albumin polypeptide or an amino acid sequence that is derived from a serum albumin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.
