Craig Geoffrey Freeman;Christopher Richard Parish;Charmaine Simeonovic
发明人:
Christopher Richard Parish,Charmaine Simeonovic,Craig Geoffrey Freeman
申请号:
US13634254
公开号:
US20130143840A1
申请日:
2011.03.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method for inhibiting oxidative damage of islet beta cells in vivo in a subject by administering to the subject a therapeutically effective amount of heparan sulfate capable of protecting islet beta cells from reactive oxygen species or in vitro by exposing isolated islet beta cells, prior to transplantation, to a concentration of heparan sulfate that protects them from reactive oxygen species.