This invention, the between quality Characteristic cystitis and/or painfully Characteristic bladder syndrome and/or the bladder with syndrome it was related painfully and/or lower part urine path condition (LUTS) adaribumabu for dealing with (Humira) it regards use painfully. As for this invention, in regard to remedy while in the subject which needs the disposal or reduction of condition of the between quality Characteristic cystitis Humira of the effective tonnage (registered trade mark) by prescribing, manner in order you deal with or to lighten condition of the quality Characteristic cystitis and is offered. Humira (registered trade mark), it can be prescribed in particular field by known optional manner.本発明は、間質性膀胱炎および/もしくは疼痛性膀胱症候群および/もしくは膀胱疼痛症候群と関連した疼痛および/もしくは下部尿路症状(LUTS)の処置のためのアダリブマブ(HumiraTM)の使用に関する。本発明は、治療上有効な量のHumira(登録商標)を投与することによって、間質性膀胱炎の症状の処置もしくは軽減を必要とする被験体における間質性膀胱炎の症状を処置もしくは軽減するための方法を提供する。Humira(登録商標)は、当該分野で公知の任意の方法によって投与され得る。