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Materials and methods for conjugating a water soluble fatty acid derivative to a protein
专利权人:
BAXTER HEALTHCARE SA
发明人:
ROTTENSTEINER HANSPETER,TURECEK PETER,SIEKMANN JUERGEN,SCHEINECKER RICHARD
申请号:
NZ61232011
公开号:
NZ612320A
申请日:
2011.12.16
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a water soluble fatty acid derivative comprising a fatty acid or fatty acid ester attached to a water soluble linker, said fatty acid derivative stably attached to a therapeutic protein, wherein the water soluble linker comprises a water soluble polymer, at least one first functional group attached to the therapeutic protein, wherein the first functional group is an aminooxy group, and a second functional group attached to the fatty acid or fatty acid ester, wherein the second functional group is an aminooxy group.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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