The protection and accommodation system is suitable in particular for a device (C) for delivering a treatment to a patient, for instance a drug by intravenous way. The system includes: a support structure arranged to be attached in a removable manner to the patient's body and defining a cavity arranged to accommodate at least one part of the device (C), and a retaining structure associated with the support structure and arranged to be coupled with a fixing portion (W) of the delivery device (C) so as to prevent a relative movement of the fixing portion (W). The support structure is arranged, in use, for assuming a cover arrangement wherein it is superposed on—and covers—the retaining structure； and a release arrangement wherein it allows to reach the retaining structure.
