BERTRAM, Ulrike,REINHOLD, Ulrich,GROßE, Christian,HARTMANN, Carmen
申请号：
AU2020100442
公开号：
AU2020100442B4
申请日:
2020.03.23
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020100442B420200618.pdf#####Abstract: Dosage Form Providing Prolonged Release of Tapentadol Phosphoric Acid Salt The invention relates to a tablet providing prolonged release of Tapentadol, wherein Tapentadol is present in form of a salt with phosphoric acid (orthophosphoric acid), preferably as dihydrogenphosphate salt. The tablet has satisfactory mechanical properties, e.g. in terms of resistance to crushing and friability, and can be prepared under greatly facilitated tableting conditions, especially at reduced compressing force.
