PURPOSE: A composition containing a Prunella vulgaris var. lilacina extract is provided to ensure antioxidation and to prevent and treat diabetes complication. CONSTITUTION: A pharmaceutical composition which suppresses synthesis of AGEs(advanced glycation end products) contains 0.1-50 wt% of a Prunella vulgaris var. lilacina extract as an active ingredient. The extract is prepared using water. The pharmaceutical composition suppresses synthesis of AGEs and prevents and treats diabetes complication. The pharmaceutical composition prevents and treats diseases selected from Alzheimer's disease, uremia, microangiopathy, cataract, or Parkinson's disease.본 발명은 하고초 추출물을 유효성분으로 함유하는 최종당화산물 억제 효과를 가지는 조성물에 관한 것이다. 본 발명에 따른 하고초 추출물을 유효성분으로 함유하는 최종당화산물 억제 효과를 가지는 조성물은 최종당화산물 합성을 억제하여 항노화 및 당뇨합병증을 예방 및 치료할 수 있다.
