SYNTHESIS OF PULMODIL AND PULMODIL-1, TWO CHLOROPHENYLPIPERAZINE SALT DERIVATIVES, AND RHOKINASE-DEPENDENT INHIBITION ACTIVITY ON PULMONARY ARTERY ENDOTHELIUM DYSFUNCTION, MEDIAL WALL THICKNESS AND VASCULAR OBSTRUCTION THEREOF

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专利权人:

KAOHSIUNG MEDICAL UNIVERSITY

发明人:

CHEN, ING JUN,陈英俊,陳英俊

申请号：

TW098114474

公开号：

TWI368513B

申请日:

2009.04.30

申请国别(地区):

TW

年份:

2012

代理人:

摘要：

The bright Ti Gong mono- Seed compounds of this Hair have such as formula one and formula two one of them structure it includes monochloro-benzene base piperazine Which Class derivatives,Wherein Lemon lemons acid (Citrate) Department in Which acid (HCl) the With formulas two in formula one is derived from a Yellow purine compounds and a piperazine (piperazine) compound.本發明提供一種化合物,其包含一氯苯基哌嗪之鹽類衍生物,具有如式一及式二其中之一的結構,其中式一中之鹽酸(HCl)與式二中之檸檬酸(Citrate)係衍生自一黃嘌呤化合物及一哌嗪(piperazine)化合物。

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/