Gregory Paul Roth,Ricardo Garcia Correa,Pasha Moeenuddin Khan,John Christian Reed
申请号：
US13207325
公开号：
US20120046329A1
申请日:
2011.08.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are compositions and methods relating to modulators of Nod-like Receptors NOD1 (NLRC1) and NOD2 (NLRC2) signaling. Further provided are methods of identifying modulators of Nod-like Receptors NOD1 and NOD2 activity. Further provided are compositions and methods for treating or preventing inflammation, including diseases associated with inflammation such as inflammatory bowel diseases (Crohns disease, ulcerative colitis), pancreatitis, arthritis, asthma, psoriasis. Alzheimers disease, cardiovascular disease (arteritis), diabetes, and sepsis.
