Use of opioid antagonists to attenuate endothelial cell proliferation and migration

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专利权人:

The University of Chicago

发明人:

Moss, Jonathan,Lingen, Mark,Garcia, Joe G.N.,Singleton, Patrick A.

申请号：

AU2013205180

公开号：

AU2013205180A1

申请日:

2013.04.14

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013205180A120130516.pdf#####ABSTRACT The invention provides methods of attenuating, eg. inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.1/28 ME morphine r~~naloxone M= MNTX * MNTX + IuM morphine VEEF IL 403020BS AVMU Concentlatlon (uM) FIG. I

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