Problem to be solved: to provide an agent that enhances the expression of IL-6 and has a high immune induction effect.An IL-6 expression promoter that combines CpG oligopes with a CpG motif and immunosynergistic Oligodeoxyribonucleic DNA having a sequence of 90% or more homology with sequences shown in specific sequences.It is possible to provide an accelerator to express IL-6, which is an inflammatory cytokine, and an immunoinducer containing the accelerator.No selection【課題】IL-6の発現を亢進し、高い免疫誘導効果を有する、剤の提供。【解決手段】CpGモチーフを有するCpG-オリゴDNAと、特定の配列に示される配列と相同性が90%以上の塩基配列を有する免疫相乗オリゴDNAと、を組み合わせてなる、IL-6発現促進剤。【効果】炎症性サイトカインであるIL-6を高発現させる促進剤、及び当該促進剤を含む免疫誘導剤を提供することが可能になる。【選択図】なし