Use of PACAP to treat viral infections in aquatic organisms

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专利权人:

セントロ デ インジエニエリア ジエネテイカ イ バイオテクノロジア

发明人:

エストラーダ ガルシア、マリオ、パブロ,ルゴ ゴンザレス、フアナ、マリア,カルピオ ゴンザレス、ヤミラ,タファーラ ピネイロ、カロリーナ

申请号：

JP2013541202

公开号：

JP5997702B2

申请日:

2011.11.30

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention relates to the use of pituitary adenylate cyclase activating polypeptide (PACAP) in the treatment of viral diseases and infectious diseases caused by viruses in aquatic organisms. PACAP, alone or combined with an antiviral molecule, demonstrated its effectiveness by increasing the survival of fish or crustaceans infected by viruses when it was administered orally, by injection or by immersion baths. Furthermore, it was observed that treated organisms keep or increase its weight as compared to infected and non-treated organisms. PACAP or PACAP-containing combinations decreased the viral load in tissues and organs susceptible to viral infections as it was determined by RT-PCR.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/