The present disclosure relates to compositions comprising a peptide with improved solubility and the methods of achieving the same. In one embodiment, the present composition comprises at least one peptide, a pH modifier present at a concentration of less than 1.0 mM, and a pharmaceutically acceptable carrier. The composition may further comprise other components such as immunomodulator adjuvant. Methods of preparing the present compositions and methods of treating a subject by administering the present compositions were also disclosed.本發明係關於包含具有提高之溶解度的肽之組合物及獲得其之方法。在一個實施例中，本發明組合物包含至少一種肽、以小於1.0 mM之濃度存在的pH調節劑及醫藥學上可接受之載劑。該組合物可進一步包含其他組分，諸如免疫調節劑佐劑。亦揭示製備本發明組合物之方法及藉由投與本發明組合物治療受試者之方法。
