The present invention relates to 2,3-dihydroimidazo(1,2-c)quinazoline derivatives as inhibitors of P13K kinase for the treatment or prophylaxis of a disease, particularly for the treatment of cancers and their metastases.La présente invention concerne des inhibiteurs de kinase PI3K pour le traitement ou la prophylaxie dune maladie, notamment le traitement de cancers ou de leurs métastases.