Koc-Kan Ho,Andrew Laird Roughton,Irina Neagu,Jui-Hsiang Chan,Nasrin Ansari,Michelle Lee Morris,Yajing Rong,Michael Ohlmeyer,Andrew John Cooke,Andrew Stanley Edwards,David Jonathan Bennett
申请号:
US12194146
公开号:
US08314091B2
申请日:
2008.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to N-benzyl,N′-arylcarbonylpiperazine derivatives having the general formula Ito pharmaceutical compositions comprising the same, and to the use of a these N-benzyl,N′-arylcarbonylpiperazine derivatives for the manufacture of a medicament for treating or preventing atherosclerosis and related disorders associated with cholesterol and bile acids transport and metabolism.