Novel compounds are disclosed that have a Formula represented by thefollowing: wherein X, R1, R2a, R2b, R2c, R3aR3b, R4a, R4b, R 4c, and ml are as described herein. The compounds may beprepared as pharmaceutical compositions, and may beused for the prevention and treatment of a variety of conditions in mammalsincluding humans, including by way of non- limitingexample, cachexia, osteoporosis, sarcopenia, a decline in libido and/or sexualdysfunction.